Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization
نویسندگان
چکیده
منابع مشابه
Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization
Skin permeability is widely considered to be mechanistically implicated in chemically-induced skin sensitization. Although many chemicals have been identified as skin sensitizers, there have been very few reports analyzing the relationships between molecular structure and skin permeability of sensitizers and non-sensitizers. The goals of this study were to: (i) compile, curate, and integrate th...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2015
ISSN: 0041-008X
DOI: 10.1016/j.taap.2014.12.013